| Autor: |
ANDRESEN, D., BETHGE, K.-P., BOISSEL, J.-P., VON LETTNER, E.-R., PEYRIEUX, J.-C., SCHRöDER, R., TIETZE, U. |
| Zdroj: |
European Heart Journal; Jun1990, Vol. 11 Issue 6, p529-536, 8p |
| Abstrakt: |
In 378 placebo patients enrolled in the European Infarction Study (EIS), a secondary prevention study after acute myocardial infarction, 24-h baseline Holier monitoring was done 14 to 31 days after MI, and the relationship of electrical (ventricular arrhythmias) and mechanical (clinical signs of ventricular dysfunction ) risk factors was analysed on the basis of mortality during the subsequent 2 years of follow-up. There was a rather low overall 2-year mortality rate of 6.9%. Consecutive arrhythmias (ventricular pairs and runs of ventricular premature beats) and left-ventricular dysfunction alone were associated with a low mortality of 4.0% and 3.6%, respectively. However, the combination of both defined a high-risk group characterized by a 2-year mortality rate of 16.7%. Additionally, the risk of dying was dependent on the frequency of consecutive arrhythmias: 22.2% of the patients with > 10 ventricular pairs per day died during the follow-up period in contrast to 9.9% of those with only 1–10 ventricular pairs per day. Thus, only the combination of electrical and mechanical risk factors, and especially the frequency of consecutive VPB, is helpful in identifying a subgroup of post MI patients with poor clinical outcome. An intervention study should restrict itself to this risk population only. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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