Aluminium toxicity during regular haemodialysis.
| Autor: | Elliott, H.L., Dryburgh, Frances, Fell, G.S., Sabet, S., Macdougall, A.I. |
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| Zdroj: | British Medical Journal; 4/29/1978, Vol. 1 Issue 6120, p1101, 3p, 1 Chart, 2 Graphs, 1 Map |
| Abstrakt: | In the west of Scotland the incidence of dialysis encephalopathy has been confined to three geographical areas where the concentration of aluminium in the water supply is greatly increased owing to the addition of aluminium sulphate. Eight patients with encephalopathy who dialysed at home in these areas had greatly increased serum aluminium concentrations, and a significant correlation was found between serum aluminium concentrations and the concentrations of aluminium in the water supply. This study provides further evidence that the dialysis encephalopathy syndrome is due to aluminium intoxication, the major source of aluminium being the water supply from which dialysis fluid is prepared. Evidence is accumulating to suggest that the dialysis encephalopathy syndrome is due to aluminium intoxication,[1-2] arising primarily from aluminium contamination of the domestic water supply.[3-4] In the west of Scotland the incidence of dialysis encephalopathy has been confined to three regions where the aluminium concentration of the water supply is relatively high; no case has occurred in Glasgow, where aluminium concentrations in water are negligible. We analysed the concentrations of aluminium and other elements in domestic water supplies in the west of Scotland dialysis area, and measured serum aluminium concentrations in patients receiving dialysis in this area. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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