Polyspecific Self-Reactive Antibodies in Individuals Infected with Human Immunodeficiency Virus Facilitate T Cell Deletion and Inhibit Costimulatory Accessory Cell Function.

Autor: Zhi-qin Qang, Orlikowsky, Thorsten, Bapat, Abhijit S., Rayanade, Ravi J., Soo Young Yang, Hoffmann, Michael K., Horowitz, Harold W., Beom-Ik Hahn, Trejo, Valia, Mittler, Robert S.
Předmět:
Zdroj: Journal of Infectious Diseases; 10/1/99, Vol. 180 Issue 4, p1072-1079, 8p, 41 Graphs
Abstrakt: Describes the presence of self-reacting antibodies in HIV-positive persons. Action on destroying human T cells in tissue culture; Reactivity with lymphocytes; Details of how exogenous costimulatory stimuli can reverse the inhibition.
Databáze: Complementary Index