Functional Asymmetry of the Cerebral Hemispheres: Its Role in the Pathogenesis of Ectromelia and Melanoma in (CBAxC57BL/6)F1 Mice.

Autor:	Abramov, V. V., Gontova, I. A., Ignatiev, I. M., Gelfgat, E. L., Kozlov, V. A.
Předmět:	CEREBRAL dominance CEREBRAL hemispheres LABORATORY mice MELANOMA NEUROLOGICAL disorders
Zdroj:	Neuroscience & Behavioral Physiology; Sep2010, Vol. 40 Issue 7, p733-736, 4p
Abstrakt:	The aim of the present work was to identify the role of functional asymmetry in the cerebral hemispheres in the pathogenesis of infectious and oncological pathology in (CBAxC57BL/6)F1 mice. Mice with lefthemisphere dominance of motor functions (“right-handers”) were found to be more resistant to infection with ectromelia virus and to show slower growth of tumors after subcutaneous injection of B-16 melanoma than animals with right-hemisphere dominance of motor control (“left-handers”). Thus, this report provides the first evidence for the role of functional asymmetry of the nervous system in the pathogenesis of ectromelia and melanoma (B-16) in (CBAxC57BL/6)F1 mice. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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