Primary chemotherapy in strongly suspected yolk sac tumor of the ovary.

Autor: Kawai, M., Ohno, Yasumasa, Shibata, Daijiro, Niwa, Yoshimitsu, Suzuki, Yuka, Kajiyama, Hiroaki, Kitagawa, Takeshi, Wakahara, Yasunori, Kakihara, Masaki, Arii, Yoshitaro
Zdroj: International Journal of Clinical Oncology; Feb1999, Vol. 4 Issue 1, p48-51, 4p
Abstrakt: We report a case of a right ovarian tumor measuring 10.8 × 10 × 8.5 cm (diagnosed as a yolk sac tumor) in a 31-year-old nulligravid woman with serum α-fetoprotein (AFP) level of 25 000 ng/ml and pleural effusion. Seven courses of primary chemotherapy (PVB; cisplatin, vinblastine, bleomycin) were given from May 16 to November 11, 1994. No surgical procedures were conducted. After the second course of PVB, the pleural effusion resolved; after the third course, the tumor disappeared, and after the fourth course, serum AFP decreased to the normal range. At the true of writing (May 11, 1998), the patient is in good health without recurrence, with an AFP level below 20 ng/ml. This paper reports, for the first time, a patient with yolk sac tumor in whom remission was achieved by primary chemotherapy alone. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz: