Efficacy of radiosynovectomy of the knee in rheumatoid arthritis: Evaluation with magnetic resonance imaging.

Autor: Alonso-Ruiz, A., Pérez-Ruiz, F., Calabozo, M., Saez, F., Pijoan, J., Ruiz-Lucea, E., Aretxabala, I., Ríos, G.
Zdroj: Clinical Rheumatology; Jul1998, Vol. 17 Issue 4, p277-281, 5p
Abstrakt: The intra-articular injection of a radiopharmaceutical agent (radiosynovectomy) produces a reduction of the synovial inflammatory process. The inflammed synovial membrane can be identified with magnetic resonance imaging after the intravenous administration of gadolinium (MRI-Gd). A 6-month prospective study was carried out in 10 patients with rheumatoid arthritis after radiosynovectomy of the knee. The efficacy was evaluated with clinical parameters and MRI-Gd. A progressive amelioration of synovial effusion, pain, articular range of mobility, total leucocytes count in synovial fluid and synovial membrane thickness through MRI-Gd was observed. The global efficacy was considered to be good in six patients, fair in three and bad in one. The study shows for the first time that MRI-Gd allows the evaluation of the response of the synovial membrane to radiosynovectomy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index