Immunosuppressive Therapy of Chronic Myocarditis in Children: Three Cases and the Design of a Randomized Prospective Trial of Therapy.

Autor: Schmaltz, A.A., Demel, K.P., Kallenberg, R., Neudorf, U., Kandolf, R., Klingel, K., Bültmann, B.
Zdroj: Pediatric Cardiology; May1998, Vol. 19 Issue 3, p235-239, 5p
Abstrakt: Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone resulted in the normalization of echocardiographic findings. Based on these observations, a randomized, multicenter treatment study of chronic myocarditis in children (TCMC) has been initiated. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index