| Autor: |
Walter, S. H., Bertz, Hartmut, Gerling, Jürgen |
| Zdroj: |
Graefe's Archive of Clinical & Experimental Ophthalmology; Jun2000, Vol. 238 Issue 6, p472-476, 5p |
| Abstrakt: |
Background: Cyclosporin A (CsA) is widely used as a prophylactic and therapeutic agent against graft-versus-host disease after bone marrow transplantation. Under this condition optic neuropathy has been found and considered as a possible side effect of cyclosporin A. Case report: A 52-year-old man presented with bilateral optic disc swelling and visual loss 6 months after bone marrow transplantation. Cyclosporin A was the only medication with a known neurotoxic side effect. After cessation of cyclosporin A and treatment with oral prednisone, vision improved within 2 months. Optic disc swelling ameliorated within 6 months but partial optic atrophy developed. Discussion: Cyclosporin A given after bone marrow transplantation may have caused bilateral optic neuropathy in our patient. Microangiopathy of the optic nerve may be the pathogenetic mechanism. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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