| Autor: |
Kravchenko, L., Avren'eva, L., Guseva, G., Posdnyakov, A., Tutel'yan, V. |
| Zdroj: |
Bulletin of Experimental Biology & Medicine; Jun2001, Vol. 131 Issue 6, p544-547, 4p |
| Abstrakt: |
Experiments on Wistar rats showed that feeding a ration containing 0.1% concentrate of food indoles (indole-3-carbinole and ascorbigen) for 3 weeks increased activity of phases I and II xenobiotic metabolism enzymes in the liver and intestinal mucosa and weakened the toxic effects of trichothecene T-2 mycotoxin. Activity of the key enzymes of T-2 detoxification, microsomal carboxylesterase and UDP-glucuronosyl transferase, was 1.5-2-fold higher in rats receiving T-2 toxin against the background of indole-enriched diet compared to toxin-treated rats kept on standard ration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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