Synthesis of 4-alkyl-substituted 1,2,3,4-tetrahydropyrimidin-2-ones by the Biginelli reaction.

Autor: Shutalev, A., Sivova, N.
Zdroj: Chemistry of Heterocyclic Compounds; Jul1998, Vol. 34 Issue 7, p848-851, 4p
Abstrakt: p-Toluenesulfinic acid is an effective catalyst for condensation of acetoacetic ester with urea and aliphatic or aromatic aldehydes, leading to formation of 4-substituted 6-methyl-5-ethoxycarbonyl-1,2,3,4-tetrahydropyrimidin-2-ones. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index