Modified Oligonucleotides Containing 1-β-D-Galactopyranosylthymine: Synthesis and Substrate Properties.

Autor: Ermolinsky, B., Fomitcheva, M., Efimtseva, E., Mikhailov, S., Esipov, D., Boldyreva, E.F., Korobko, V., van Aerschot, A., Herdewijn, P.
Zdroj: Russian Journal of Bioorganic Chemistry; Jan2002, Vol. 28 Issue 1, p50-57, 8p
Abstrakt: A convenient method of regioselective introduction of 1-β- D-galactopyranosylthymine into oligonucleotides was developed and the substrate properties of the modified oligonucleotides were investigated in the enzymatic reactions of formation and hydrolysis of internucleotide bonds. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index