Improved outcome in thoracoabdominal aortic aneurysm repair: the role of cerebrospinal fluid drainage.

Autor: Fleck, Tatjana, Koinig, Herbert, Moidl, Reinhard, Czerny, Martin, Hamilton, Carole, Schifferer, Arno, Jelen, Marian, Wolner, Ernst, Grabenwoger, Martin, Fleck, Tatjana M
Zdroj: Neurocritical Care; Feb2005, Vol. 2 Issue 1, p11-16, 6p
Abstrakt: Introduction: To evaluate the protective effect and the optimum duration of cerebrospinal fluid drainage (CSFD) during and after thoracoabdominal aortic aneurysm (TAAA) repair.Methods: From April 2001 to October 2003, we retrospectively compared 17 (n = 17) consecutive patients who have been electively operated on by Martin Grabenwoger for left heart bypass and selective perfusion of the visceral and renal organs.Results: The first 7 patients had CSFD for 72 hours; the duration of CSFD was increased to 100 hours in the remaining 10 patients. Median drained cerebrospinal fluid (CSF) volume was 680 milliliters in the 72-hour group versus 1441 milliliters in the 100-hour group. A characteristic increase in CSF volume was noted between POD No. 2 and POD No. 4 indicating persistent spinal cord edema. Univariate and multivariate analysis demonstrated that CSFD for 100 hours is a significant predictor for decreased incidence of late onset paraplegia (p < 0.001). The overall incidence of postoperative neurological deficit was 17.6% (3 of 17). There was one patient (6%) who developed permanent paraplegia and two patients (12%) with transient paraplegia. These patients sustained late-onset paraplegia 72 hours after surgery for removal of a CSFD device. Complete motor function could be restored after re-insertion of a CSFD device. In one patient, permanent paraplegia was evident after awakening from anesthesia. Because of technical difficulties, only two intercostal arteries could be re-implanted, which was obviously not sufficient to restore spinal cord perfusion. In contrast, no neurological deficit occurred in patients in whom a CSFD instrument was left for 100 hours.Conclusion: The extended duration of CSFD may lower the risk of late-onset paraplegia and could improve outcome in patients undergoing thoracoabdominal aortic surgery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz: