IL-7 is critical for homeostatic proliferation and survival of naive T cells.

Autor: Tan, Joyce T., Dudl, Eric, LeRoy, Eric, Murray, Richard, Sprent, Jonathan, Weinberg, Kenneth I., Surh, Charles D.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 7/17/2001, Vol. 98 Issue 15, p8732, 6p, 8 Graphs
Abstrakt: Examines the role of interleukin-7 (IL-7) for homeostatic proliferation and survival of naive T cells. Response of naive T cells during contact with self-MHC/peptide ligand; Disappearance of naive T cells upon adoptive transfer into IL-7-host; Restoration of homeostatic proliferation in IL-7.
Databáze: Complementary Index