QSAR STUDIES ON ADENOSINE KINASE INHIBITORS.

Autor: Agrawal, Vijay K., Singh, Kamana, Khadikar, Padmakar V.
Zdroj: Medicinal Chemistry Research; Jul2004, Vol. 13 Issue 6/7, p479-496, 18p
Abstrakt: The present study reports QSAR study on adenosine kinase inhibitors pyrrolo[2, 3-d] pyrimidine nucleoside analogous. The equalized electronegativity along with a large pool of topological indices are used for the purpose. The regression analysis has shown that equalized electronegativity is a good parameter which in combination with topological indices and an indicator parameter gave excellent model. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index