Predicting Dissolution Profiles.

Autor: Mattes, Robert, Root, Denise, Chaoju Xiao, Yinqi Zhou, Johnson, James, Shukla, Atul
Předmět:
Zdroj: Pharmaceutical Processing; Oct2009, Vol. 24 Issue 10, p14-17, 4p
Abstrakt: The article presents a study which predicts the dissolution profile of intact tablets using the diffuse transmission near-infrared (NIR) spectroscopy. Study shows that the NIR prediction has provided a fast as well as an exact means of non-destructively assessing tablets, which is in step with the initiatives of Process Analytical Technology (PAT). The authors conclude that the finding implies a relief of laboratory workload from dissolution testing.
Databáze: Complementary Index