| Autor: |
Airaghi, Lorena, Garofalo, Letizia, Cutuli, Maria Grazia, Delgado, René, Carlin, Andrea, Demitri, Maria Teresa, Badalamenti, Salvatore, Graziani, Giorgio, Lipton, James M., Catania, Anna |
| Zdroj: |
Nephrology Dialysis Transplantation; Aug2000, Vol. 15 Issue 8, p1212-1216, 5p |
| Abstrakt: |
Background. Clinical and/or laboratory signs of systemic inflammation occur frequently in patients undergoing long‐term haemodialysis. It is likely, therefore, that a compensatory release of endogenous anti‐inflammatory molecules occurs to limit host reactions. The aim of the present research was to determine if the potent anti‐inflammatory peptide α‐melanocyte‐stimulating hormone (α‐MSH), a pro‐opiomelanocortin derivative, is increased in plasma of haemodialysis patients. Because endotoxin and cytokines induce α‐MSH in vivo and in vitro, we also measured plasma concentrations of endotoxin, interleukin‐6 (IL‐6), and tumour necrosis factor α (TNF‐α), and the two circulating products of activated monocytes, nitric oxide (NO) and neopterin. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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