| Autor: |
Harding, I., MacGowan, A. P., White, L. O., Darley, E. S. R., Reed, V., Darley, E S |
| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); Jun2000, Vol. 45 Issue 6, p835-841, 7p |
| Abstrakt: |
Logistic regression analysis was performed on data drawn from a clinical trials database for Staphylococcus aureus septicaemia treated with teicoplanin. Variables analysed were age, body weight, mean pre-dose and post-dose serum teicoplanin concentrations, mean dose (mg or mg/kg body weight) and combination versus monotherapy. Only two variables correlated with clinical outcome at a significance level better than 0.05: age (P = 0.012) and mean pre-dose serum concentration (P = 0.010). The probability of successful treatment declined with age and increased with mean pre-dose serum concentration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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