The Free Radical Scavenger Alpha-Phenyl-Tert-Butyl Nitrone Aggravates Hippocampal Apoptosis and Learning Deficits in Experimental Pneumococcal Meningitis.

Autor: Loeffler, Jutta M., Ringer, Ralph, Hablutzel, Martin, Tauber, Martin G., Leib, Stephen L.
Předmět:
Zdroj: Journal of Infectious Diseases; 1/15/2001, Vol. 183 Issue 2, p247, 6p, 1 Black and White Photograph, 3 Graphs
Abstrakt: Presents a study which evaluated the effects of adjuvant therapy with the radical scavenger alpha-phenyl-tert-butyl nitrone on brain injury and learning function in an infant rat model of pneumococcal meningitis. Materials and methods used; Characteristics of the disease; Histopathologic aspects of cortical and hippocampal injury; Conclusions.
Databáze: Complementary Index