| Autor: |
Lorenzen, Johan, Meyer-Olson, Dirk, Haubitz, Marion, Witte, Torsten, Bange, Franz, Schmidt, Reinhold, Stoll, Matthias |
| Předmět: |
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| Zdroj: |
Clinical Rheumatology; Jun2009 Supplement 1, Vol. 28, p39-41, 3p, 1 Graph |
| Abstrakt: |
A 55-year-old woman with systemic lupus erythematosus was admitted with fever of unknown origin. She had been on an immunosuppressive regimen for the past 8 years including steroids and Azathioprine. Laboratory parameters revealed a markedly elevated C-reactive protein of 189 mg/l, antinuclear antibodies of 1:2,560, a hemoglobin level of 9.0 g/dl, and a severe lymphopenia (total lymphocytes 49.4/μl, CD4+ cells 2/μl, CD8+ cells 7/μl). Neither blood culture samples nor computed tomography and magnetic resonance imaging of the chest and abdomen nor a trans-esophageal echocardiography revealed positive results. A bone marrow biopsy did not show signs of hematologic disease, but revealed a small granuloma rife with acid-fast bacilli, which were later confirmed to be Mycobacterium genavense by gene sequencing. To our knowledge, this is the first case involving M. genavense infection in a patient with systemic lupus erythematosus. In contrast to other reports regarding disseminated M. genavense infection, the patient is still alive and well. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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