| Autor: |
Kölbel, Tilo, Strandberg, Karin, Donath, Tobias, Mattiasson, Ingrid, Stenflo, Johan, Lindblad, Bengt |
| Předmět: |
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| Zdroj: |
Vascular & Endovascular Surgery; Apr/May2008, Vol. 42 Issue 2, p135-140, 6p |
| Abstrakt: |
Increased thrombin activation was documented in patients with abdominal aortic aneurysm (AAA). Activated protein C-protein C inhibitor (APC-PCI) complex, a new biological marker of thrombin generation, was measured in a population of 232 patients with AAA and a control group, and the association between aneurysm size, growth rate, and APC-PCI was studied. The patients were divided into cohorts according to AAA diameter and compared with a control group. APC-PCI was significantly higher in all AAA cohorts (n = 232; median, 0.36 μg/L; 10th to 90th percentile, 0.18-1.01) compared with the control group (n = 41; median, 0.19 μg/L; 10th to 90th percentile, 0.11-0.31; P
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| Databáze: |
Complementary Index |
| Externí odkaz: |
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