| Autor: |
Petraco, Nicholas D.K., Proni, Gloria, Jackiw, Jennifer J., Sapse, Anne‐Marie |
| Předmět: |
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| Zdroj: |
Journal of Forensic Sciences; Nov2006, Vol. 51 Issue 6, p1267-1275, 9p, 7 Diagrams, 3 Charts |
| Abstrakt: |
Ninhydrin is one of the most widely used reagents for chemical development of fingerprints on porous surfaces. The detection is based on the reaction of ninhydrin with a monoacidic component of the fingerprint to form an intensively colored compound named Ruhemann's Purple. A computational study of the mechanisms and reaction energetics of the formation of Ruhemann's Purple from ninhydrin and alanine is presented. Such a study is significant from a forensic science point of view because of the strong interest in the forensic chemistry and law enforcement communities in developing alternatives to the current generation of ninhydrin like chemicals for the detection and development of latent fingerprints. Information about the mechanism of reaction between ninhydrin and amino acids can ultimately help to design compounds with stronger chromo-fluorogenic properties in aid of detecting fingerprints at crime scenes. The three most accepted mechanisms of formation have been considered using ab initio quantum mechanical calculations. At relatively high temperature (∼100°C) all three mechanisms are energetically feasible. However since it is recommended that forensic analyses be performed at room temperature, a revised mechanism is proposed for the formation of Ruhemann's Purple under this condition. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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