Screening for Chlamydia trachomatis infection using the BDProbeTec ET Chlamydia trachomatis amplified DNA assay on urine in a GUM clinic setting: a simple, fast and cost-effective alternative.
| Autor: | Browning, M. R., Corden, S., Mitchell, B., Westmoreland, D. |
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| Předmět: |
CHLAMYDIA trachomatis
CHLAMYDIA STUDY & teaching of medicine URINALYSIS CULTURE MEDICAL care THERAPEUTICS DNA analysis CHLAMYDIA infections COMPARATIVE studies COST effectiveness GENITOURINARY diseases OUTPATIENT services in hospitals RESEARCH methodology MEDICAL cooperation DISEASES in men RESEARCH COST analysis EVALUATION research PREDICTIVE tests NUCLEIC acid amplification techniques |
| Zdroj: | International Journal of STD & AIDS; Jul2001, Vol. 12 Issue 7, p430-436, 7p, 2 Charts |
| Abstrakt: | This study compared the BDProbeTec ET Chlamydia trachomatis amplified DNA assay on urine specimens with culture of genital swabs for the detection of C. trachomatis in patients attending the Department of Genitourinary Medicine (GUM), Cardiff Royal Infirmary. Almost twice as many patients tested positive by BDProbeTec ET than by culture. A similar difference was found for both males and females. The case notes of those patients positive by BDProbeTec ET alone were analysed and a significantly greater number were found to have risk indicators for C. trachomatis infection when compared with age and sex comparable controls, providing clinical validation of our findings. The BDProbeTec ET assay was easy to use, more importantly, the test format features an internal control integral with every sample. The cost per true positive was calculated as comparable with culture. We conclude that the BDProbeTec ET assay is a superior alternative to culture for identifying patients infected with C. trachomatis in the GUM clinic setting. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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