Effect of Neonatal Injection of Sodium Glutamate and Diethylnitrosamine on Hepatocarcinogenesis, Reproductive and Adrenocortical Systems of Male Mice.

Autor: E. G. Kuznetsova, T. G. Amstislavskaya, V. V. Bulygina, S. I. Il’nitskaya
Zdroj: Bulletin of Experimental Biology & Medicine; Jun2005, Vol. 139 Issue 6, p711-714, 4p
Abstrakt: Abstract Neonatal injection of sodium glutamate before injection of diethylnitrosamine decreased the number of tumor nodes in the liver of male mice, decreased the weight of the testes and adrenals and blood level of testosterone (but increased blood level of corticosterone), impaired recovery of diethylnitrosamine-disturbed sexual motivation in half of males. Anticarcinogenic effect of sodium glutamate is explained by feminization of males under its effect. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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