| Autor: |
Christoph CH Huwiler, Martin MH Halter, Kurosch KR Rezwan, Didier DF Falconnet, Marcus MT Textor, Janos JV Vörös |
| Předmět: |
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| Zdroj: |
Nanotechnology; Dec2005, Vol. 16 Issue 12, p3045-3052, 8p |
| Abstrakt: |
The production of hierarchical nanopatterns (using a top-down microfabrication approachcombined with a subsequent bottom-up self-assembly process) will be an important tool inmany research areas. We report the fabrication of silica nanoparticle arrays onlithographically pre-patterned substrates suitable for applications in the field ofnanobiotechnology. Two different approaches to reach this goal are presented anddiscussed: in the first approach, we use capillary forces to self-assemble silica nanoparticleson a wettability contrast pattern by controlled drying and evaporation. This allowsthe efficient patterning of a variety of nanoparticle systems and—under certainconditions—leads to the formation of novel branched structures of colloidal lines,that might help to elucidate the formation process of these nanoparticle arrays.The second approach uses a recently developed chemical patterning method thatallows for the selective immobilization of functionalized sub-100 nm particles atdistinct locations on the surface. In addition, it is shown how these nanocolloidalmicro-arrays offer the potential to increase the sensitivity of existing biosensingdevices. The well-defined surface chemistry (of particle and substrate) and theincreased surface area at the microspots, where the nanoparticles self-assemble,make this patterning method an interesting candidate for micro-array biosensing. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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