| Autor: |
Gumustekin, Kenan, Ciftci, Mehmet, Coban, Abdulkadir, Altikat, Sayit, Aktas, Omer, Gul, Mustafa, Timur, Handan, Dane, Senol |
| Předmět: |
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| Zdroj: |
Journal of Enzyme Inhibition & Medicinal Chemistry; Oct2005, Vol. 20 Issue 5, p497-502, 6p, 1 Chart, 1 Graph |
| Abstrakt: |
Effects of nicotine, and nicotine + vitamin E on glucose 6-phosphate dehydrogenase (G-6PD) activity in rat muscle, heart, lungs, testicle, kidney, stomach, brain and liver were investigated in vivo and in vitro on partially purified homogenates. Supplementation period was 3 weeks (n = 8 rats per group): nicotine [0.5 mg/kg/day, intraperitoneal ( ip )]; nicotine + vitamin E [75 mg/kg/day, intragastric ( ig )]; and control group (receiving only vehicle). The results showed that nicotine (0.5 mg/kg, ip ) inhibited G-6PD activity in the lungs, testicle, kidney, stomach and brain by 12.5% (p [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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