Facile Preparation of tert-Butyl 1-tert-Butoxycarbonylaminocyclopent-3-enecarboxylate from Inexpensive Starting Materials .

Autor: Oleg Larionov, Sergei Kozhushkov, Armin de Meijere
Předmět:
Zdroj: Synthesis; 2005, Vol. 2005 Issue 1, p158-160, 3p
Abstrakt: 1,5-C,C-Cycloalkylation of tert-butyl acetoacetate (1) with cis-1,4-dichloro-2-butene (2) followed by the haloform reaction of the product in NaOH solution and subsequent Curtius degradation in tert-butyl alcohol furnished tert-butyl 1-tert-butoxycarbonylaminocyclopent-3-enecarboxylate (5) in 32% overall yield. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index