| Autor: |
Kopelman, Doron, Blevis, Ira, Iosilevsky, Galina, Reznik, Alla, Chaikov, Alex, Weiner, Naor, Israel, Ora, Hashmonai, Moshe |
| Předmět: |
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| Zdroj: |
European Journal of Nuclear Medicine & Molecular Imaging; Oct2005, Vol. 32 Issue 10, p1217-1224, 8p, 10 Black and White Photographs, 1 Chart, 1 Graph |
| Abstrakt: |
Purpose: Radioguided surgery depends on the intra-operative detection of radiolabelled tissues. This is currently accomplished with hand tools capable of providing a tone signal, depending on the proximity and direction of a radioactive source in relation to the probe. The advantages of visual images of radiolabelled tissues are well recognised, but satisfactory means of acquiring such images intra-operatively are not yet available. The goal of this study was to examine the performance of a newly developed intra-operative gamma camera, compact enough to be a hand tool and capable of yielding a visual image of the source field. Methods: The study was performed in the laboratory with a phantom consisting of a water bath and small hollow spheres (1–2 cm in internal diameter) filled with 99mTc (1–5 μCi/cc), placed in different configurations within the bath. For comparison, studies were also performed using a standard intra-operative gamma probe, and others using a standard single-head high-resolution gamma camera. Results: Compared with the gamma probe, the intra-operative camera was found to possess a superior ability to distinguish small, deep and weakly localised radioactivity sources from background. By acquiring images from different angles, it allowed a 3D understanding of multiple radioactive sources. It detected ‘cold’ defects within a ‘hot’ radiolabelled sphere. It discriminated a weak source located near a much ‘hotter’ radioactivity source, similar to discrimination with the standard gamma camera, and discerned localised sources against a background of radioactivity. Conclusion: It is anticipated that the high imaging potential of the camera tested in this study will offer clinical advantages. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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