| Autor: |
Kumar, Deepak, Satam, Nishikant, Namboothiri, Irishi N. N. |
| Zdroj: |
Synthesis; Jan2025, Vol. 57 Issue 1, p71-83, 13p |
| Abstrakt: |
The magnesium-mediated addition of bromoform to conjugated electron-deficient alkenes and imines, such as para -quinone methides (p -QMs) and aurone-derived azadienes, respectively, is reported here for the first time. While p -QMs undergo exclusive and hitherto unreported 1,6-addition of bromoform to afford benzylic tribromomethylated diarylmethanes, aurone-derived azadienes undergo both 1,2- and 1,4-additions to furnish α- and γ-tribromomethylamines. A mechanism involving the intermediacy of the tribromomethyl radical has been proposed based on control experiments and EPR studies. Representative synthetic transformations have also been carried out. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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