| Abstrakt: |
Aim: We aimed to assess low to mid-range left ventricular ejection fraction (LVEF) predictors at one-month follow-up in STEMI patients using baseline electrocardiography (ECG) and standard laboratory tests. Methods: In this retrospective cross-sectional study, 130 STEMI patients (79% male, mean age: 57.2 ± 11.9 years) were enrolled. Multivariate linear regression analysis determined the relationship of baseline 12-lead ECG and clinical/laboratory parameters with LVEF at the 1st-month follow-up visit. Results: The mean LVEF of the patients at the 1st-month follow-up visit was 51.8 ± 8.7%. There was a significant negative correlation between age (r = -0.206)*, peak CK-MB level (-0.0411)**, QTc interval (r = -0.209)*, STE amount (mV) (r = -0.286)**, V5–6 RWPT (r = -0.238)** and aVR RWPT (r = -0.466)** with LVEF (*p < 0.05; **p < 0.01). The aVR R wave peak time (RWPT) (OR: 0.88, p < 0.01) and peak CK-MB level (OR: 0.91, p < 0.01) were the two most important predictors of low-to-mid-range LVEF (<%50) during mean 38 ± 5 days follow-up after STEMI. Conclusion: Our study results suggested that the baseline aVR RWPT and peak CK-MB level were associated with low-to-mid-range LVEF at the 1st-month follow-up after STEMI. These parameters may be used in the risk stratification of STEMI patients to develop LV remodeling during follow-up. Plain Language Summary In this study, we aimed to examine the parameters in electrocardiography (ECG) and blood tests that predict the risk of developing heart failure in patients who had a heart infarction and whose coronary arteries were completely blocked. In this retrospective study, we included 130 heart attack patients. We used various statistical methods to determine which parameters could be predictive in patients who developed heart failure. For this purpose, we used ECG parameters and blood tests that increase during a heart infarction. We showed that the time indicating ventricular activation in the aVR derivation of the ECG and the peak creatine kinase (CK)-MB level, which increases during a heart infarction and is measured in the blood test, are the most critical parameters for the development of heart failure. These parameters can be used in the risk stratification of heart infarction patients for the development of heart failure during follow-up. Article highlights Our study assessed the baseline electrocardiographic (ECG) and biochemical predictors of short-term (one-month) left ventricular remodeling and low-to-mid-range left ventricular ejection fraction (LVEF of <50%) after ST-segment elevation myocardial infarction (STEMI). Age, peak creatine kinase (CK)-MB level, QTc interval, ST-segment elevation (STE) amount (mV), V5–6 R-wave peak time (RWPT) and aVR RWPT were negatively and significantly correlated with LVEF. Baseline aVR RWPT (OR:0.88, p < 0.01) and peak CK-MB (OR:0.99, p < 0.01) level during index admission were found as the most critical indicators of low-to-mid-range LVEF at one-month follow-up after STEMI. The aVR RWPT on admission 12-lead ECG and peak CK-MB level may be used to predict LV remodeling and LVEF reduction in patients with STEMI. The clinicians may consider using these parameters in risk stratification and close follow-up of STEMI patients as those tests are simple, widely available and cheap. [ABSTRACT FROM AUTHOR] |
