Organisms isolated in aerobic vaginitis and it's antibiotic sensitivity pattern in patients presenting with vaginal discharge in a tertiary care hospital.

Autor: Abinaya, A. G., Praveena, B., Sailaja, M., Reddy, B. Shanthi
Zdroj: European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 3, p672-679, 8p
Abstrakt: Introduction: Bacterial vaginosis is the most common outpatient clinical condition in gynecology department; globally Diagnosis of bacterial vaginosis is by amsel's criteria during clinical examination, nugents criteria of gram stain and culture analysis can help to detect the exact pathogen and to start the accurate treatment. The aim of this study is to know the aerobic bacteriology of bacterial vaginosis and their antibiotic susceptibility pattern.Materials and Methods: A total of 363 patients participated in this descriptive cross sectional study was between the age group of 15 to 55 years. Their samples were collected and processed as per guidelines by performing gram stain and culture & sensitivity testing method. Patient details such as age, socioeconomic status, relapse of bacterial vaginosis, number of partners, type of discharge, associated symptoms and signs, and microbiological details were tabulated in an excel sheet to evaluate further. Results: Gram positive cocci are highly susceptible to gentamicin(100%), high level gentam icin(100%), vancomycin(82.8%) followed by linezolid(71.4%), clindamycin(60%), amoxiclav(48.6%) and least sensitive to azithromycin(28.6%). Gram negative bacilli are highly susceptible to amikacin(88.9%), meropenem(85.7%), cefipime(69.2%), followed by piperacillin tazobactam(60%), cotrimoxazole (53.5%), ciprofloxacin (50%), ofloxacin (44.4%), cefotaxime (40.7%), doxycycline (33.3%) and they were least sensitive to ceftriaxone (27.8%). Between the age group of 15 - 28 years, E.coli and Staphylococcus aureus were the most common organism isolated, followed by klebsiella pneumonia, Enterococci, CONS, Candida, Acinetobacter and Klebsiella oxytoca. Between the age group of 29 - 55 years, E.coli was the most common organism isolated, followed by Klebsiella pneumoniae, Enterococci and Staphylococci aureus. Conclusion: This study emphasizes the need to understand the aerobic pathogens associated with vaginitis especially in the reproductive age group to prevent adverse complications seen during pregnancy and labour. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index