| Autor: |
Murugesan, Vetrivelan, Syam, Anagha, Anantharaj, Guru Vigknesh, Rasappan, Ramesh |
| Předmět: |
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| Zdroj: |
Chemical Communications; 12/11/2024, Vol. 60 Issue 95, p14049-14052, 4p |
| Abstrakt: |
Hydroalkylation of terminal alkynes via C–H activation is the most atom-economical and straightforward method for synthesizing alkenes. They remain confined to using C(sp2)–H or activated C(sp3)–H bonds. A chelating group enabled the alkenylation of C(sp3)–H bonds, resulting in E alkenes. Protocols by which alkenylation of unactivated C(sp3)–H bonds occurs without a chelating group via metal-hydride or radical pathways remain unknown. Our cobalt-HAT catalysis achieves the desired Z alkene with excellent regio- and diastereoselectivity via C–H activation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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