| Autor: |
Kovacs, Timea, Wan, Angie, Patel, Tejesh |
| Předmět: |
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| Zdroj: |
Cutis; Oct2024, Vol. 114 Issue 4, pE26-E28, 3p |
| Abstrakt: |
The article in Cutis discusses a case of an elderly woman with hyperkeratotic papules and black macules on her hands, which were diagnosed as Acral Hemorrhagic Darier Disease (DD). DD is a rare autosomal-dominant genodermatosis caused by mutations in the ATP2A2 gene, leading to abnormal calcium signaling in keratinocytes. The patient responded well to treatment with retinoids and topical corticosteroids, showing a reduction in hyperkeratotic plaques and resolution of acral hemorrhagic lesions. The differential diagnosis included acrokeratosis verruciformis of Hopf, porphyria cutanea tarda, bullous lichen planus, and hemorrhagic lichen sclerosus. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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