| Autor: |
Shepelenko, K. E., Gnatiuk, I. G., Chernyshev, V. M. |
| Předmět: |
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| Zdroj: |
Russian Journal of General Chemistry; Oct2024, Vol. 94 Issue 10, p2586-2592, 7p |
| Abstrakt: |
A new approach for the preparation of 3-alkenyl furans and thiophenes by selective C3–H alkenylation of furan-2- and thiophene-2-carboxylic acids with internal alkynes has been developed, and novel 3-alkenylated furans and thiophenes have been synthesized and characterized. The main advantages of the developed approach are the use of readily available substrates in which the COOH function serves as a traceless in situ removable directing group, the high regioselectivity of the C3–H alkenylation, which provides easy access to C3-alkenylated furans and thiophenes with highly reactive C2–H and C5–H bonds that are difficult to access by previously reported methods, and the use of a relatively inexpensive [RuCl2(p-cymene)2] precatalyst in the absence of copper and silver promoters. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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