| Autor: |
Jiang, Yanan, Meng, Fanying, Ge, Zhenghong, Zhou, Yuxiao, Fan, Zhen, Du, Jianzhong |
| Zdroj: |
Journal of Materials Chemistry B; 12/7/2024, Vol. 12 Issue 45, p11596-11610, 15p |
| Abstrakt: |
Insufficient development of new antibiotics and the rise in antimicrobial resistance are putting the world at risk of losing curative medicines against bacterial infection. Quorum sensing is a type of cellular signaling for cell-to-cell communication that plays critical roles in biofilm formation and antimicrobial resistance, and is expected to be a new type of effective target for drug resistant bacteria. In this review we highlight recent advances in bioinspired peptide/polyamino acid assemblies as quorum sensing inhibitors across various microbial communities. In addition, existing obstacles and future development directions of peptide/polyamino acid assemblies as quorum sensing inhibitors were proposed for broader clinical applications and translations. Overall, quorum sensing peptide/polyamino acid assemblies could be vital tools against bacterial infection and antimicrobial resistance. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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