| Autor: |
Shen, Ruipeng, Chen, Ya-xiong, Chen, Yating, Sayed, Zahid Nasim, Yi, Meirong, Sun, Chunlin, Zhang, Baoxin, Fang, Jianguo |
| Předmět: |
|
| Zdroj: |
Chemical Communications; 12/4/2024, Vol. 60 Issue 93, p13774-13777, 4p |
| Abstrakt: |
Vicinal dithiol proteins (VDPs) facilitate cellular redox homeostasis, modulate protein synthesis and participate in post-translational modifications through the dynamic equilibrium of dithiol and disulfide bonds. Herein, an activatable red emitting fluorescent probe, VDP-red, is developed for detecting VDPs. With the aid of this probe, we have discovered for the first time a reduction in the levels of reduced VDPs in a stroke mouse model. This work provides a fresh viewpoint for understanding stroke mechanisms. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
