| Autor: |
Shi, Honggang, Tuerxun, Kahaer, Yusupu, Aizizaimu, Yusupu, Zainuer, Xu, Qilin, Jia, Yibin, Maimaitireyimu, Musitaba, Maimaitiaili, Tuerhongaji, Muhetajiang, Muzaipaer, Lin, Jiaxin, Ma, Chengmin, Li, Xiaofeng, Wu, Yuanquan, Su, Yonghui |
| Předmět: |
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| Zdroj: |
PLoS Neglected Tropical Diseases; 11/13/2024, Vol. 18 Issue 11, p1-12, 12p |
| Abstrakt: |
Background: Surgical intervention is a crucial treatment for hepatic cystic echinococcosis. However, the choice between radical and conservative surgery remains controversial. This study aimed to compare the perioperative outcomes and hospitalization costs between radical and conservative surgery for hepatic cystic echinococcosis. Method: A retrospective cohort study was conducted on patients undergoing surgical treatment at the First People's Hospital of Kashi Prefecture from July 1, 2012, to October 1, 2023. Propensity score-matching analysis was utilized to mitigate patient selection bias between the two surgical groups. Result: Of the 434 patients included, 324 underwent conservative surgery and 110 underwent radical surgery. After propensity score-matching, 182 conservative surgery and 102 radical surgery patients were compared. Radical surgery patients experienced longer operative time, higher intraoperative blood loss, increased blood transfusion, and higher costs compared to conservative surgery patients. However, no differences were observed in short-term outcomes, including overall morbidity, death, bile leak, effusion, pulmonary infection, incision infection, intestinal obstruction, ICU stay, abdominal drainage time, and postoperative hospital stays. Conclusion: This study suggests that radical surgery is associated with greater surgical complexity and higher hospitalization costs, while it doesn't offer a significant short-term advantage. Conservative surgery may be a viable option in resource-limited settings or for patients unsuitable for complex procedures. Further research with long-term follow-up is needed to determine the optimal approach. Author summary: Surgical outcomes and hospitalization costs are crucial considerations for surgeons when selecting a treatment approach. This retrospective study compared perioperative outcomes and hospitalization costs between radical and conservative surgery for hepatic cystic echinococcosis. We analyzed data from patients treated at the First People's Hospital of Kashi Prefecture from July 1, 2012, to October 1, 2023, using propensity score matching to minimize selection bias. Our findings revealed that while radical surgery entailed longer operative times, greater blood loss, and higher costs, there were no significant differences in short-term outcomes such as mortality, complication rates, or length of hospital stay compared to conservative surgery. This suggests that conservative surgery may be a viable alternative, especially in resource-limited settings where the complexity and high costs of radical surgery pose challenges. Importantly, our study focused on short-term outcomes and hospitalization costs. Future research should incorporate long-term follow-up to assess the recurrence rates associated with each surgical approach. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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