| Autor: |
Sau, Biyanka, Sarkar, Arijit, Mukherjee, Shuvankar, Ghosh, Somosree |
| Předmět: |
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| Zdroj: |
European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 4, p498-502, 5p |
| Abstrakt: |
Background: Pseudomonas aeruginosa is one of the most common bacteria to cause infections in both community and hospital settings. Its ability to survive in varied environmental conditions, various virulence factors, and multi-drug resistance patterns has helped the organism cause difficulty in treating infection. Objectives: The objective of the study was to know the prevalence of Pseudomonas isolates and in particular P. aeruginosa isolates in varied clinical specimens and to assess the antimicrobial susceptibility patterns of P. aeruginosa as well as its magnitude of multidrug resistance (MDR) in a tertiary care hospital in Eastern India. Materials & Methods: A total of 206 confirmed isolates of Pseudomonas isolates from various clinical samples were studied. Identification and speciation of the isolates and their antibiotic susceptibility testing were determined by conventional and automated methods (Vitek 2 compact). Results: Out of the 206 isolates of Pseudomonas, 143 isolates were P. aeruginosa, the majority (44.75%) were from pus samples. Resistance to amikacin and gentamycin was 34% and 36%, ciprofloxacin and levofloxacin were 32.8% and 35%, Resistance to ceftazidime and cefepime were 43.4% and 49.6%. Imipenem and meropenem showed 37% and 35% resistance, respectively. Resistance to piperacillin-tazobactam was only 35%. Conclusion: There is increased resistance to cephalosporins, aminoglycosides, carbapenems and beta lactamase inhibitors. To restrict the inappropriate use of antimicrobial agents and the development of MDR, there is a need to continuously monitor and document the prevailing resistance pattern in a particular geographical area. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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