Effects of hemodialysis on biochemical and endocrinological parameters in patients with renal failure attending in tertiary care hospital at, pmch, Patna.

Autor: Deb, Nayana, Sinha, Madhu, Sagar, Satyendu
Předmět:
Zdroj: European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 4, p382-383, 2p
Abstrakt: Objective: Present study was conducted to evaluate the effects of hemodialysis on biochemical and endocrinological parameters in patients with renal failure. Materials and methods: A cohort of 50 patients with end-stage renal disease (ESRD) undergoing hemodialysis was analyzed. Blood samples were collected pre- and post-dialysis to measure biochemical (electrolytes, urea, creatinine) and endocrinological (parathyroid hormone, erythropoietin, insulin) parameters. Statistical analysis was conducted to determine the significance of changes. Results: Hemodialysis significantly reduced serum urea and creatinine levels. Electrolyte imbalances, such as hyperkalemia, were corrected. Endocrinological changes included a significant reduction in parathyroid hormone and an increase in erythropoietin levels, while insulin levels showed variable responses. Conclusions: Hemodialysis effectively normalizes several biochemical imbalances in ESRD patients. Endocrinological parameters also show significant changes, highlighting the need for ongoing monitoring and management in these patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index