Evaluation of Adiponectin Level and Other Clinical Variables in Iraqi Adolescence Type 1 Diabetic Patients.

Autor: Akram, Raghda Shams, Jafer, Abeer Abass, Jassem, Hiba Swadi
Předmět:
Zdroj: Bahrain Medical Bulletin; Sep2024, Vol. 46 Issue 3, p2223-2226, 4p
Abstrakt: Childhood and adolescence are the times when T1DM develops more frequently than adults. This study investigated the relationship between Adiponectin levels and some clinical variables in Iraqi adolescents with T1DM. The study included 90 subjects. Two groups were created for this study based on the initial mutant cell's lineage.: 45 Adolescence of Type I diabetes mellitus ranging in age (12-17 years) and control group 45 Participants in this study were matched for age and sex and appeared healthy. There was a highly substantial increase of rise weight, height, FBS, PPBS, TG, and HOMA-IR in T1DM adolescents in comparison to groups under control. There is a significant increase in BMI, TC and insulin level IR in T1DM Adolescence in contrast to groups under control. There was an appositive correlation between Adiponectin level and weight, BMI, and Insulin level and a highly positive correlation coefficient with FBS. PPBS, TC, TG, AIC, HOMA-IR while negative correlation with LDL in adolescent T1DM patients. We conclude that the decrease in adiponectin in patients with type 1 diabetes and adolescent children is an indicator of the appearance of many early diabetes complications in them, and this is considered a risk indicator for many diseases and thus leads to metabolic dysfunction in diabetic patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index