Spatial Structure and Anti-Inflammatory Activity of 5-N-Arylaminocarbonyl-6-Aryl-4-Methyl-1,2,3,6-Tetrahydropyrimidine-2-Thiones.

Autor: Buzmakova, N. A., Zamaraeva, T. M., Rudakova, I. P., Dmitriev, M. V.
Předmět:
Zdroj: Pharmaceutical Chemistry Journal; Aug2024, Vol. 58 Issue 5, p738-741, 4p
Abstrakt: The anti-inflammatory activity of 17 derivatives of 5-N-arylaminocarbonyl-6-aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thiones was studied. The molecular structure of one of them was established. Ten compounds that inhibited the inflammatory reaction in experimental animals in the range 56-81% were identified. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index