Covalent immobilization of bovine serum albumin on the magnetic chitosan biopolymer for the Cu ions decoration and investigation of its catalytic efficiency.

Autor: Rafiee, F., Salekmokhtari, N.
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Zdroj: Polymer Bulletin; Nov2024, Vol. 81 Issue 16, p14641-14662, 22p
Abstrakt: In this work, chitosan was cross-linked with dialdehyde chitosan to stabilize it and also provide aldehyde segments for the further functionalization with bovine serum albumin. Then, the magnetization procedure was done through the treatment of hybrid polymer with Fe3O4 nanoparticles. BSA was covalently immobilized on the magnetic CS-CSOX biopolymer through condensation of amine groups of amino acid units with the aldehyde functional groups of dialdehyde chitosan. N-terminal peptides, histidine and tryptophan residues of BSA and also the thiol side chain of cysteine and sulfur donor atom of methionine may be as proper binding sites for the copper ions coordination. The catalytic efficiency of Fe3O4@CS-BSA-Cu nanocatalyst was examined in the synthesis of 5-substituted tetrazoles and also 1,4-diaryl-1,2,3-triazoles. The prepared nanocatalyst was separated by an external magnet and reused without significant difference in its activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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