Copper-catalyzed C(sp3)–H alkylation of fluorene with primary and secondary alcohols using a borrowing hydrogen method.

Autor: Saha, Ratnakar, Maharana, Suraj Kumar, Jana, Narayan Ch., Bagh, Bidraha
Předmět:
Zdroj: Chemical Communications; 9/21/2024, Vol. 60 Issue 74, p10144-10147, 4p
Abstrakt: Despite the limited success of copper-catalyzed alkylations, (NNS)CuCl proved to be an effective catalyst for the sp3 C–H alkylation of fluorene with alcohols. Various primary alcohols and challenging secondary alcohols were successfully used. The practical applicability of the method was effectively tested with several post-functionalization reactions. This copper-catalyzed alkylation of fluorene involved a borrowing hydrogen mechanism. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index