Photoinduced decarboxylative radical cascade alkylation/cyclization of benzimidazole derivatives with an aliphatic carboxylic acid via ligand-to-iron charge transfer.

Autor:	Xu, Yan, Wang, ChenJing, Lv, Chun, Wang, Jianjie, Zhang, Qian, Wang, Jiayang, Shen, Run-Pu, Sun, Bin, Jin, Can
Předmět:	CARBOXYLIC acid derivatives CHARGE transfer ALKYL radicals ALKYLATION BENZIMIDAZOLE derivatives RING formation (Chemistry) CARBOXYLIC acids
Zdroj:	New Journal of Chemistry; 9/7/2024, Vol. 48 Issue 33, p14684-14689, 6p
Abstrakt:	The photoinduced decarboxylative radical cascade alkylation/cyclization strategy of diverse benzimidazoles containing unactivated alkene moieties towards the synthesis of polycyclic benzimidazoles via ligand-to-metal-charge-transfer (LMCT) has been developed. Specifically, the reaction initiates the decarboxylation of alkyl carboxylic acids through light-induced charge transfer from the ligand to iron, resulting in the formation of alkyl radical centers. Moreover, the protocol has prominent features, such as a broad substrate scope, high regioselectivity, mild reaction conditions, operational simplicity and readily available air acting as the sole oxidant. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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