Abstrakt: |
Researchers from Universite Paris Cite have conducted a study on Sjogren's syndrome, an autoimmune disease characterized by chronic inflammation in the salivary and lacrimal glands. The study focused on mucosal-associated invariant T (MAIT) cells, a subset of innate-like T-cells found in mucosal tissues. The researchers found that MAIT cells were decreased in the peripheral blood of Sjogren's syndrome patients, but showed higher production of inflammatory cytokines. Tissular MAIT cells were also detected in the salivary glands of Sjogren's syndrome patients, suggesting their potential role in epithelial damage. Further research is needed to understand the exact mechanisms of MAIT cells in Sjogren's syndrome. [Extracted from the article] |