| Abstrakt: |
A study conducted at the University of Washington in Seattle explored the use of different biopolymers for the expansion of human neural stem cells (hNSCs) in 3D tissue scaffolds. The researchers found that scaffolds made of pure chitosan supported the highest adhesion and growth of hNSCs, resulting in the most viable cells with NSC marker protein expression. In contrast, the presence of other biopolymers like alginate, hyaluronic acid, or collagen induced differentiation towards immature neurons and astrocytes. These findings suggest that pure chitosan scaffolds have the potential to be used as a base material for the expansion of hNSCs in 3D. The research was funded by KYOCERA Corporation, the National Science Foundation, and the Department of Neurological Surgery at the University of Washington. [Extracted from the article] |
