Transcranial Alternating Current Stimulation in a Patient with Ataxia-Ocular Apraxia 2: a Case Report.

Autor: Cheng, Xiao-Ping, Yu, Wen-Hui, Liu, Xia, Lin, Wei, Wang, Zhao-Di, Wang, Xi-Chen, Ni, Jun, Cai, Nai-Qing, Chen, Xin-Yuan
Předmět:
Zdroj: Cerebellum; Aug2024, Vol. 23 Issue 4, p1713-1717, 5p
Abstrakt: Ataxia-ocular apraxia 2 (AOA2) is a rare neurodegenerative autosomal recessive disorder with no effective treatment. In this study, we present the case of a patient diagnosed with AOA2, who experienced walking instability and uncoordinated movement. The patient underwent transcranial alternating current stimulation (tACS) treatment for 4 weeks with follow-up after 1 month. The effectiveness of the treatment was evaluated using the International Cooperative Ataxia Rating Scale (ICARS), the Scale for the Assessment and Rating of Ataxia (SARA), the 9-Hole Peg Test (9HPT), and functional near-infrared spectroscopy (fNIRS). Following treatment, the patient's ataxia symptoms showed significant improvement and continued to be alleviated during the follow-up period, suggesting a lasting effect of tACS treatment. Our findings from this case study provide compelling evidence for the potential of tACS as a treatment option for AOA2. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index