Genotoxic effects in the buccal cells of students exposed to season-associated increase of air pollution in Prishtina urban area: a preliminary study.

Autor: Panxhaj, Djellza, Asllani, Fisnik H., Alija, Avdulla J., Dreshaj, Shemsedin, Bresgen, Nikolaus
Předmět:
Zdroj: Genetics & Applications; Jun2024, Vol. 8 Issue 1, p1-9, 9p
Abstrakt: The available monitoring data from Kosovo Environmental Protection Agency show concerning levels of the air pollution in Prishtina - the capital city of Kosovo and the most populated city in the country. Due to the air pollutants emitted mostly from the heavy traffic and the coal-fired power plants located in the vicinity, the residents of urban area in Prishtina are exposed to unhealthy air. It is reported that the situation worsens during the autumn and winter months due to more frequent smog episodes. Based on the concerns raised, the aim of the study was to assess the eventual genotoxic effects of air pollution among residents of Prishtina during the autumn and winter months. For this purpose, 29 healthy female non-smoker students (aged 20-26) were involved in this preliminary study. The first sampling of buccal cells took place beginning of November 2019 whereas the second sampling took place by the end of January 2020. Buccal cell samples were analyzed for the frequency of micronuclei and the obtained data demonstrate increased genotoxicity in a sample population as an effect of the exposure to increased air pollution levels in Prishtina urban area during the autumn and winter period. On the other hand, these preliminary data clearly indicate the need for continuing with bio-monitoring studies by extending the timeframe and increasing the number of seasons under investigation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index