| Autor: |
Madoure, Anbarasi, Srinivasan, Dharanya Gopalakrishnan, Mishra, Tejaswi, Penubarthi, Lokesh Kumar |
| Zdroj: |
BMJ Case Reports; Jun2024, Vol. 17 Issue 6, p1-3, 3p |
| Abstrakt: |
A man in his 40s with type 2 diabetes mellitus had persistent right-sided watery nasal discharge for 6months following cerebrospinal fluid (CSF) leak repair at another hospital, prompting his visit to us due to recurring symptoms. Imaging revealed a CSF leak from the mid-clivus for which revision endoscopic CSF leak repair was done. Regrettably, he developed postoperative meningitis caused by multidrug-resistant (MDR) Klebsiella pneumoniae. Managing this complex case was a challenging task due to the pathogen’s resistance to conventional drugs and the scarcity of scientific evidence. We initiated a culture-guided combination regimen with ceftazidime, avibactam, aztreonam and tigecycline. This decision stemmed from meticulous literature review and observed antibiotic synergy while testing for this organism. After 4weeks of vigilant treatment, the patient’s symptoms improved significantly, and CSF cultures were sterile. We present our approach to effectively confront and manage a challenging instance of postoperative MDR bacterial meningitis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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