| Autor: |
Jadoon, Sara, Hussain, Atif, Shaheen, Sadaf, Hayat, Nida Qasim, Javed, Sumaira, Imtiaz, Humaira |
| Předmět: |
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| Zdroj: |
Pakistan Journal of Chest Medicine; 2023, Vol. 29 Issue 2, p171-178, 8p |
| Abstrakt: |
Background: The use of electronic cigarettes, or vaping, to obtain nicotine is gaining popularity. Numerous researches have demonstrated the potential health risks and development of nicotine dependency associated with smoking electronic cigarettes. The effects of traditional and electronic cigarettes on lung tissue were evaluated in this study. Objective: The objective of the study was to determine the Lung Histomorphological changes exposed to Cigarette Smoke and Electronic Cigarette Vapors in Rats. Methodology: This study was conducted at the Women Medical College Abbottabad and Ayub Medical College Abbottabad. The study duration was six months from July 2022 to December 2022. The study was conducted on, 30 male Wistar rats collected from NIH Islamabad. Three groups of animals were used: group C was the control group, meaning it did not get any nicotine; group A received liquid vapor from electronic cigarettes; and group B rats were exposed to regular smoking. Results: Both experimental groups exhibited several abnormalities, including as collagen deposition, type II pneumocyte hyperplasia, parenchymal collapse, and an upsurge in macrophages inside a thicker alveolar septa. There was also evidence of an early elastolysis. In contrast to the group exposed to ordinary cigarette smoke, there were more a-SMA positive myofibroblasts and blood vessels, and the elastic fibers were thicker, less dense, irregular, and disordered. Conclusion: Our study concludes that using electronic cigarettes causes fewer severe histomorphological changes than smoking regular cigarettes. However, the histopathological damage caused by vaping may lead to the formation of alterations in lung tissue that obstruct gas exchange. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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