New Cardiovascular Diseases and Conditions Findings from Augusta University Described (Testosterone Deficiency Promotes Arterial Stiffening Independent of Sex Chromosome Complement).

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Zdroj: Hematology Week; 7/8/2024, p443-443, 1p
Abstrakt: New research from Augusta University in Georgia explores the role of sex hormones and sex chromosomes in cardiovascular disease. The study found that lower testosterone levels are associated with cardiovascular and cardiometabolic diseases, while testosterone replacement therapy can have beneficial effects on cardiovascular health. The researchers used male mice to investigate the impact of testosterone deprivation on arterial stiffening and vascular wall remodeling. They found that castration increased arterial stiffening and collagen deposition, particularly in mice with XX sex chromosome complement. This study highlights the potential benefits of sex hormone replacement therapy in both men and women. [Extracted from the article]
Databáze: Complementary Index